If you hit, then the system compares your skill to the appropriate skill on the target: Dodge for a Pistol or Rifle attack, or Melee Defense for a melee-style attack. The defender’s skill can raise or lower damage amount and provides the chance for a critical hit. After that, the target’s armor, special abilities, mutations, and usable items come into play, which potentially mitigates the amount of damage done. Damage is also affected by where you hit the target. A shot to the head does more damage than a hit to the leg.